Article
Rs11892031[A] on chromosome 2q37 in an intronic region of the UGT1A locus is associated with urinary bladder cancer risk.
Archives of toxicology - 1 Sept 2012
Selinski Silvia, Lehmann Marie-Louise, Blaszkewicz Meinolf, Ovsiannikov Daniel, Moormann Oliver, Guballa Christoph, Kress Alexander, Truss Michael C, Gerullis Holger, Otto Thomas, Barski Dimitri, Niegisch Günter, Albers Peter, Frees Sebastian, Brenner Walburgis, Thüroff Joachim W, Angeli-Greaves Miriam, Seidel Thilo, Roth Gerhard, Volkert Frank, Ebbinghaus Rainer, Prager Hans M, Bolt Hermann M, Falkenstein Michael, Zimmermann Anna, Klein Torsten, Reckwitz Thomas, Roemer Hermann C, Hartel Mark, Weistenhöfer Wobbeke, Schöps Wolfgang, Rizvi S Adibul Hassan, Aslam Muhammad, Bánfi Gergely, Romics Imre, Ickstadt Katja, Hengstler Jan G, Golka Klaus
Abstract excerpt
Recently, rs11892031[A] has been identified in a genome-wide association study (GWAS) to confer increased risk of urinary bladder cancer (UBC). To confirm this association and additionally study a possible relevance of exposure to urinary bladder carcinogens, we investigated the IfADo UBC study group, consisting of eight case-control series from different regions including 1,805 cases and 2,141 controls. This...
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