Article
Distinct SNP combinations confer susceptibility to urinary bladder cancer in smokers and non-smokers.
PloS one - 1 Jan 2012
Schwender Holger, Selinski Silvia, Blaszkewicz Meinolf, Marchan Rosemarie, Ickstadt Katja, Golka Klaus, Hengstler Jan G
Abstract excerpt
Recently, genome-wide association studies have identified and validated genetic variations associated with urinary bladder cancer (UBC). However, it is still unknown whether the high-risk alleles of several SNPs interact with one another, leading to an even higher disease risk. Additionally, there is no information available on how the UBC risk due to these SNPs compare to the risk of cigarette smoking and to...
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