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Article

Glucuronidation and UGT isozymes in bladder: new targets for the treatment of uroepithelial carcinomas?

Oncotarget - 10 Jan 2017

Sundararaghavan Vikram L, Sindhwani Puneet, Hinds Terry D

Abstract excerpt

Bladder cancer has been linked to numerous toxins which can be concentrated in the bladder after being absorbed into the blood and filtered by the kidneys. Excessive carcinogenic load to the bladder urothelium may result in the development of cancer. However, enzymes within the bladder can metabolize carcinogens into substrates that are safer. Importantly, these proteins, namely the UGT's (uridine...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27690298
DOI: 10.18632/oncotarget.12277
PMCID: PMC5356909

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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