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Article

Lys656Asn polymorphism of leptin receptor gene and metabolic syndrome in obese patients.

European review for medical and pharmacological sciences - 1 May 2011

De Luis D A, Gonzalez Sagrado M, Aller R, Izaola O, Conde R, Castro M J

Abstract excerpt

BACKGROUND: The etiology of common obesity is complex, because many genetic, environmental and metabolic factors might act. Alterations of the normal leptin receptor gene be involved in the development of obesity. The polymorphism on codon 656 produces a change in charge, making this change a possibility to be functional. OBJECTIVE: The aim of our study was to investigate the relationship between metabolic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 21744741

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LEPR

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