A Val227Ala substitution in the peroxisome proliferator activated receptor alpha (PPAR alpha) gene associated with non-alcoholic fatty liver disease and decreased waist circumference and waist-to-hip ratio.

Abstract excerpt

BACKGROUND AND AIM: This study analyzes the effect of the val227ala variant of the peroxisome proliferators-activated receptor-alpha (PPAR-alpha) on non-alcoholic fatty liver disease. METHODS: 79 patients with NAFLD and 63 healthy counterparts were included in the study. Body mass index (BMI), hip, waist, waist-to-hip ratio (WHR), blood pressure (BP), the percentage of body fat, total protein, albumin, ALT,...

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