Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association of nonalcoholic fatty liver disease with a single nucleotide polymorphism on the gene encoding leptin receptor.

IUBMB life - 1 Feb 2012

Swellam Menha, Hamdy Nadia

Abstract excerpt

Leptin (Lep), a 16-kDa polypeptide hormone, exerts its action through the leptin receptor (LepRb), a member of the class I cytokine receptor family. Both leptin and LepRb probably have been implicated in pathogenesis of nonalcoholic fatty liver disease (NAFLD). This study was designed to assess the role of soluble leptin and LepRb in NAFLD and to investigate whether leptin receptor gene (LepR) single nucleotide...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Case-Control Studies
Share to Fatty Liver
Share to Genetic Association Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Logistic Models

Share to Multivariate Analysis

Share to Non-alcoholic Fatty Liver Disease

Share to Protein Isoforms

Share to Receptors, Leptin

Source

Identifiers

PMID: 22215535
DOI: 10.1002/iub.597

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of nonalcoholic fatty liver disease with a single nucleotide polymorphism on the gene encoding leptin receptor.PMID 22215535Read ↗

Lys656Asn polymorphism of leptin receptor, leptin levels and insulin resistance in patients with non alcoholic fatty liver disease.Semantic proximity Read ↗

Polymorphism of human leptin receptor gene is associated with type 2 diabetic patients complicated with non-alcoholic fatty liver disease in China.Semantic proximity Read ↗

Impact of leptin receptor gene variants on risk of non-alcoholic fatty liver disease and its interaction with adiponutrin gene.Semantic proximity Read ↗

The rs2275738 variant of the adiponectin receptor 1 gene is associated with biopsy-proven nonalcoholic fatty liver disease.Semantic proximity Read ↗

INSULIN AND INSULIN RECEPTOR GENE POLYMORPHISMS AND SUSCEPTIBILITY TO NONALCOHOLIC FATTY LIVER DISEASE.Semantic proximity Read ↗

Association of adipocytokine pathway gene polymorphisms with NAFLD in obese children.Semantic proximity Read ↗

Association of adiponectin gene polymorphism with nonalcoholic fatty liver disease in Taiwanese patients with type 2 diabetes.Semantic proximity Read ↗

Association between leptin and NAFLD: a two-sample Mendelian randomization study.Semantic proximity Read ↗

Adiponectin polymorphisms and non-alcoholic fatty liver disease risk: a meta-analysis.Semantic proximity Read ↗

The LEPR K109R and Q223R Might Contribute to the Risk of NAFLD: A Meta-Analysis.Semantic proximity Read ↗

Correlation of Adiponectin Gene Polymorphisms rs266729 and rs3774261 With Risk of Nonalcoholic Fatty Liver Disease: A Systematic Review and Meta-Analysis.Semantic proximity Read ↗

RESISTIN GENE POLYMORPHISM AND NONALCOHOLIC FATTY LIVER DISEASE RISK.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.