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Article

Highly selective binding of naphthyridine with a trifluoromethyl group to cytosine opposite an abasic site in DNA duplexes.

Organic & biomolecular chemistry - 28 May 2012

Sato Yusuke, Zhang Yushuang, Seino Takehiro, Sugimoto Takashi, Nishizawa Seiichi, Teramae Norio

Abstract excerpt

We report on highly selective binding of a naphthyridine derivative with a trifluoromethyl group to cytosine opposite an abasic site in DNA duplexes; the binding-induced fluorescence quenching is applicable to the analysis of a C-related single-base mutation in DNAs amplified by PCR.

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PMID: 22526917
DOI: 10.1039/c2ob25513h

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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