Fluorescence emission detection of single-nucleotide polymorphisms by a naphthyridine-benzofurazan conjugate.

doi:10.1093/nass/nrm149

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Article

Fluorescence emission detection of single-nucleotide polymorphisms by a naphthyridine-benzofurazan conjugate.

Nucleic acids symposium series (2004) - 1 Jan 2007

Satake Hiroyuki, Nishizawa Seiichi, Teramae Norio

Abstract excerpt

We have successfully developed a class of ligand that exhibits a fluorescence-enhancement upon binding to pyrimidine bases opposite an AP site in DNA duplexes. The present ligand, Naph-c3-DBD, in which DBD (7-N,N-dimethylaminosulfonylbenzo-2-oxa-1,3-diazole) is connected to 2-amino-7-methyl-1,8-naphthyridine by a propylene linker, is capable of selectively binding to pyrimidine bases over purine bases, and the...

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PMID: 18029704
DOI: 10.1093/nass/nrm149

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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