Article
Ribosome engineering to promote new crystal forms.
Acta crystallographica. Section D, Biological crystallography - 1 May 2012
Selmer Maria, Gao Yong-Gui, Weixlbaumer Albert, Ramakrishnan V
Abstract excerpt
Crystallographic studies of the ribosome have provided molecular details of protein synthesis. However, the crystallization of functional complexes of ribosomes with GTPase translation factors proved to be elusive for a decade after the first ribosome structures were determined. Analysis of the packing in different 70S ribosome crystal forms revealed that regardless of the species or space group, a contact...
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