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Article

X-ray crystal structures of the WT and a hyper-accurate ribosome from Escherichia coli.

Proceedings of the National Academy of Sciences of the United States of America - 22 Jul 2003

Vila-Sanjurjo Antón, Ridgeway William K, Seymaner Veysel, Zhang Wen, Santoso Steve, Yu Kexin, Cate Jamie H Doudna

Abstract excerpt

Protein biosynthesis on the ribosome requires accurate reading of the genetic code in mRNA. Two conformational rearrangements in the small ribosomal subunit, a closing of the head and body around the incoming tRNA and an RNA helical switch near the mRNA decoding site, have been proposed to select for complementary base-pairing between mRNA codons and tRNA anticodons. We determined x-ray crystal structures of the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 12853578
DOI: 10.1073/pnas.1133380100
PMCID: PMC166372

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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