Rapid Detection of <i>rpoB</i> Gene Mutations Conferring Rifampin Resistance in Mycobacterium tuberculosis

Abstract excerpt

Multidrug-resistant Mycobacterium tuberculosis strains are widespread and present a challenge to effective treatment of this infection. The need for a low-cost and rapid detection method for clinically relevant mutations in Mycobacterium tuberculosis that confer multidrug resistance is urgent, particularly for developing countries. We report here a novel test that detects the majority of clinically relevant...

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