Article
Solid-phase sequence scanning for drug resistance detection in tuberculosis.
Molecular and cellular probes - 1 Apr 1999
Head S R, Parikh K, Rogers Y H, Bishai W, Goelet P, Boyce-Jacino M T
Abstract excerpt
DNA chip arrays hold considerable promise for diagnostic sequencing of polymerase chain reaction (PCR) products. To date, however, arrays have been relatively expensive, complex to use and difficult to interpret, preventing their adaptation to the clinical lab. A moderate density array method has been developed that enables efficient, easy-to-interpret and robust solid-phase PCR product sequencing. Here, the...
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