Article
Receptor for advanced glycation end-product (RAGE) gene polymorphism 2245G/A is associated with pro-inflammatory, oxidative-glycation markers and sRAGE in diabetic retinopathy.
Gene - 1 Jun 2013
Ng Zhi Xiang, Kuppusamy Umah Rani, Iqbal Tajunisah, Chua Kek Heng
Abstract excerpt
BACKGROUND: Receptor for advanced glycation end-product (RAGE) gene polymorphism 2245G/A is associated with diabetic retinopathy (DR). However, the mechanism on how it affects the disease development is still unclear. AIM: This study aims to investigate the relationship between 2245G/A RAGE gene polymorphism and selected pro-inflammatory, oxidative-glycation markers in DR patients. METHODS: A total of 371...
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