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Article

Soluble RAGE, diabetic nephropathy and genetic variability in the AGER gene.

Archives of physiology and biochemistry - 1 Apr 2008

Kanková Katerina, Kalousová Marta, Hertlová Miluse, Krusová Darja, Olsovský Jindrich, Zima Tomás

Abstract excerpt

Diabetes mellitus, especially when complicated with decline of renal function due to diabetic nephropathy (DN), is associated with accumulation of advanced glycation end products (AGEs) exerting their adverse effects via receptor of AGE (RAGE). Soluble RAGE (sRAGE) is a truncated form of RAGE functioning as an inhibitor of AGE-mediated signalling. We studied relationships between sRAGE, renal function and genetic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18615900
DOI: 10.1080/13813450802033818

Genes

AGER

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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