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Article

Cumulative effect and predictive value of genetic variants associated with type 2 diabetes in Han Chinese: a case-control study.

PloS one - 1 Jan 2015

Qian Yun, Lu Feng, Dong Meihua, Lin Yudi, Li Huizhang, Dai Juncheng, Jin Guangfu, Hu Zhibin, Shen Hongbing

Abstract excerpt

BACKGROUND: Genome-wide association studies (GWAS) have identified dozens of single nucleotide polymorphisms (SNPs) associated with type 2 diabetes risk. We have previously confirmed the associations of genetic variants in HHEX, CDKAL1, VEGFA and FTO with type 2 diabetes in Han Chinese. However, the cumulative effect and predictive value of these GWAS identified SNPs on the risk of type 2 diabetes in Han Chinese...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 25587982
DOI: 10.1371/journal.pone.0116537
PMCID: PMC4294637

Genes

CDKAL1
FTO
HHEX
KCNQ1
VEGFA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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