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Article

A genome-wide association study identifies novel risk loci for type 2 diabetes.

Nature - 22 Feb 2007

Sladek Robert, Rocheleau Ghislain, Rung Johan, Dina Christian, Shen Lishuang, Serre David, Boutin Philippe, Vincent Daniel, Belisle Alexandre, Hadjadj Samy, Balkau Beverley, Heude Barbara, Charpentier Guillaume, Hudson Thomas J, Montpetit Alexandre, Pshezhetsky Alexey V, Prentki Marc, Posner Barry I, Balding David J, Meyre David, Polychronakos Constantin, Froguel Philippe

Abstract excerpt

Type 2 diabetes mellitus results from the interaction of environmental factors with a combination of genetic variants, most of which were hitherto unknown. A systematic search for these variants was recently made possible by the development of high-density arrays that permit the genotyping of hundreds of thousands of polymorphisms. We tested 392,935 single-nucleotide polymorphisms in a French case-control cohort....

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Identifiers

PMID: 17293876
DOI: 10.1038/nature05616

Genes

ALX4
EXT2
HHEX
IDE
KIF11

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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