Article
Replication of genome-wide association studies of type 2 diabetes susceptibility in Japan.
The Journal of clinical endocrinology and metabolism - 1 Aug 2008
Horikawa Yukio, Miyake Kazuaki, Yasuda Kazuki, Enya Mayumi, Hirota Yushi, Yamagata Kazuya, Hinokio Yoshinori, Oka Yoshitomo, Iwasaki Naoko, Iwamoto Yasuhiko, Yamada Yuichiro, Seino Yutaka, Maegawa Hiroshi, Kashiwagi Atsunori, Yamamoto Ken, Tokunaga Katsushi, Takeda Jun, Kasuga Masato
Abstract excerpt
BACKGROUND: In Europeans and populations of European origin, several groups have recently identified novel type 2 diabetes susceptibility genes, including FTO, SLC30A8, HHEX, CDKAL1, CDKN2B, and IGF2BP2, none of which were in the list of functional candidates. OBJECTIVE AND DESIGN: The aim of this study was to replicate in a Japanese population previously identified associations of single nucleotide polymorphisms...
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