Article
Variations in/nearby genes coding for JAZF1, TSPAN8/LGR5 and HHEX-IDE and risk of type 2 diabetes in Han Chinese.
Journal of human genetics - 1 Dec 2010
Zhou Dai-zhan, Liu Yun, Zhang Di, Liu Si-min, Yu Lan, Yang Yi-feng, Zhao Teng, Chen Zhuo, Kan Meng-yuan, Zhang Zuo-feng, Feng Guo-yin, Xu He, He Lin
Abstract excerpt
Several genetic loci (JAZF1, CDC123/CAMK1D, TSPAN8/LGR5, ADAMTS9, VEGFA and HHEX-IDE) were identified to be significantly related to the risk of type 2 diabetes and quantitative metabolic traits in European populations. Here, we aimed to evaluate the impacts of these novel loci on type 2 diabetes risk in a population-based case-control study of Han Chinese (1912 cases and 2041 controls). We genotyped 13...
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