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Article

Evaluation of OPRM1 variants in heroin dependence by family-based association testing and meta-analysis.

Drug and alcohol dependence - 8 Oct 2007

Glatt Stephen J, Bousman Chad, Wang Richard S, Murthy Kenton K, Rana Brinda K, Lasky-Su Jessica A, Zhu Shao C, Zhang Ruimin, Li Jianhua, Zhang Bo, Li Jixiang, Lyons Michael J, Faraone Stephen V, Tsuang Ming T

Abstract excerpt

OPRM1, which codes for the mu-opioid receptor, is the most frequently studied candidate gene for opioid dependence. Despite numerous allelic association studies, no definitive conclusion has been reached regarding the role of OPRM1 polymorphisms in determining risk for opioid dependence. We attempted to resolve this by conducting a family-based association study and meta-analysis which may be more robust and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 17416470
DOI: 10.1016/j.drugalcdep.2007.02.022
PMCID: PMC2012941

Genes

OPRM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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