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Transglutaminase 3: The Involvement in Epithelial Differentiation and Cancer

30 Aug 2020

Abstract excerpt

Transglutaminases (TGMs) contribute to the formation of rigid, insoluble macromolecular complexes, which are essential for the epidermis and hair follicles to perform protective and barrier functions against the environment. During differentiation, epidermal keratinocytes undergo structural alterations being transformed into cornified cells, which constitute a highly tough outermost layer of the epidermis, the...

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PMID: 32872587
DOI: 10.3390/cells9091996

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