Article
Desmoglein 3 anchors telogen hair in the follicle.
Journal of cell science - 1 Sept 1998
Koch P J, Mahoney M G, Cotsarelis G, Rothenberger K, Lavker R M, Stanley J R
Abstract excerpt
Little is known about the function of desmosomes in the normal structure and function of hair. Therefore, it was surprising that mice without desmoglein 3 (the autoantigen in pemphigus vulgaris) not only developed mucous membrane and skin lesions like pemphigus patients, but also developed hair l...
Topics
- Acantholysis
- Alopecia
- Animals
- Antibodies
- Cadherins
- Cell Adhesion
- Desmoglein 3
- Desmosomes
- Disease Models, Animal
- Hair
- Hair Follicle
- Humans
- Immunohistochemistry
- Keratinocytes
- Mice
- Mice, Knockout
- Pemphigus
- Phenotype