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Article

Transglutaminases in autoimmune and inherited skin diseases: The phenomena of epitope spreading and functional compensation.

Experimental dermatology - 1 Aug 2018

Kárpáti Sarolta, Sárdy Miklós, Németh Krisztián, Mayer Balázs, Smyth Neil, Paulsson Mats, Traupe Heiko

Abstract excerpt

Transglutaminases (TGs) are structurally and functionally related enzymes that modify the post-translational structure and activity of proteins or peptides, and thus are able to turn on or switch off their function. Depending on location and activities, TGs are able to modify the signalling, the function and the fate of cells and extracellular connective tissues. Besides mouse models, human diseases enable us to...

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Source

Identifiers

PMID: 28940785
DOI: 10.1111/exd.13449

Genes

TGM1
TGM3
TGM5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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