Article
Association of the C242T polymorphism in the NADPH oxidase p22 phox gene with carotid atherosclerosis in Slovenian patients with type 2 diabetes.
Molecular biology reports - 1 Dec 2012
Letonja Marija Santl, Nikolajević-Starčević Jovana, Batista Daniela Cristina Branco, Osredkar Joško, Petrovič Danijel
Abstract excerpt
Oxidative stress plays an important role in the pathogenesis of diabetes and its complications. Genetic variations of enzymes producing reactive oxygen species could change their activity, thus contributing to the susceptibility to oxidative stress. The aim of this study was to examine the role of the NADPH oxidase C242T polymorphism in the development of carotid atherosclerosis in patients with type 2 diabetes....
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