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Article

CYBA C242T gene polymorphism and flow-mediated vasodilation in a population of young adults: the Cardiovascular Risk in Young Finns Study.

Journal of hypertension - 1 Jul 2007

Fan Meng, Raitakari Olli T, Kähönen Mika, Juonala Markus, Hutri-Kähönen Nina, Marniemi Jukka, Rontu Riikka, Pörsti Ilkka, Viikari Jorma, Lehtimäki Terho

Abstract excerpt

OBJECTIVE: Nicotinamide adenine dinucleotide phosphate (NADPH) oxidase is a major source of the superoxide anion that contributes to decreased nitric oxide bioavailability in the vasculature. The C242T polymorphism of the CYBA gene that encodes p22phox, a component of NADPH oxidase, has been found to modulate superoxide production. We examined the relationship of the C242T polymorphism with endothelial-dependent...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17563559
DOI: 10.1097/HJH.0b013e32810bfe58

Genes

CYBA

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Click a neighbor to travelStep 1 · 12 closest

CYBA C242T gene polymorphism and flow-mediated vasodilation in a population of young adults: the Cardiovascular Risk in Young Finns Study.PMID 17563559Read ↗

The C242T p22phox polymorphism and endothelium-dependent vasodilation in subjects with hypercholesterolaemia.Semantic proximity Read ↗

The C242T CYBA polymorphism of NADPH oxidase is associated with essential hypertension.Semantic proximity Read ↗

Functional effect of the C242T polymorphism in the NAD(P)H oxidase p22phox gene on vascular superoxide production in atherosclerosis.Semantic proximity Read ↗

Relationship between C242T polymorphism and arterial stiffness in an apparently healthy population.Semantic proximity Read ↗

C242T CYBA polymorphism of the NADPH oxidase is associated with reduced respiratory burst in human neutrophils.Semantic proximity Read ↗

CYBA gene variants as biomarkers for coronary artery disease.Semantic proximity Read ↗

The A640G CYBA polymorphism associates with subclinical atherosclerosis in diabetes.Semantic proximity Read ↗

The association between cigarette smoking and carotid intima-media thickness is influenced by the -930A/G CYBA gene polymorphism: the Cardiovascular Risk in Young Finns Study.Semantic proximity Read ↗

Association of nicotinamide adenine dinucleotide phosphate oxidase p22phox gene 549C>T polymorphism with coronary artery disease.Semantic proximity Read ↗

The C242T CYBA polymorphism as a major determinant of NADPH oxidase activity in patients with cardiovascular disease.Semantic proximity Read ↗

NAD(P)H oxidase p22phox Gene C242T polymorphism and lipoprotein oxidation.Semantic proximity Read ↗

The 242T variant of the CYBA gene polymorphism increases the risk of coronary artery disease associated with cigarette smoking and hypercholesterolemia.Semantic proximity Read ↗

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