Article
Association of Two CD44 Polymorphisms with Clinical Outcomes of Gastric Cancer Patients
Asian Pacific journal of cancer prevention : APJCP - 26 May 2018
Bitaraf Seyed Mohammadreza, Mahmoudian Reihaneh Alsadat, Abbaszadegan Mohammadreza, Mohseni Meybodi Anahita, Taghehchian Negin, Mansouri Atena, Forghanifard Mohammad Mahdi, Memar Bahram, Gholamin Mehran
Abstract excerpt
Objective: CD44 is an important cell adhesion molecule that plays a key role in growth, invasion, proliferation and metastasis of cancer cells. CD44 protein over-expression is associated with a poor prognosis of gastric cancer (GC) and previous studies have shown that CD44 gene polymorphisms could affect survival and recurrence. In this study, we tested the hypothesis that polymorphisms impacting on the CD44...
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