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Article

The association between rs2228226 and postoperative clinical outcomes in gastric adenocarcinoma: a retrospective study.

BMC medical genomics - 11 Feb 2025

Wu Haowen, Li Xinxiong, Dang Yuan, Zhang Yawei, Zhang Zaizhong, Zhang Bowen, Cai Qinglong, Wang Lie, Wang Meiping, Xiao Chunhong

Abstract excerpt

BACKGROUND: This study aims to investigate the differences in postoperative prognosis associated with the single nucleotide polymorphism (SNP) rs2228226 (G > C) in gastric adenocarcinoma (GAC) patients. METHODS: This study enrolled 661 patients with locally advanced (pT4a) GAC after surgery. DNA was extracted from their tissues and genotyped for rs2228226 using a MassARRAY Analyzer. Based on the patients'...

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Topics

Humans

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Stomach Neoplasms

Male

Female

Polymorphism, Single Nucleotide

Middle Aged

Adenocarcinoma

Retrospective Studies

Aged

Prognosis

Treatment Outcome

Adult

Postoperative Period

Genotype

Source

Open in PubMed Open full text

Identifiers

PMID: 39934772
DOI: 10.1186/s12920-025-02102-x
PMCID: PMC11817046

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