Article
Heterozygosity of stromelysin-1 (rs3025058) promoter polymorphism is associated with gastric cancer.
Indian journal of cancer - 1 Jan 2000
Krishnaveni D, Bhayal A C, Shravan K P, Jyothy A, Pratibha N, Venkateshwari A
Abstract excerpt
BACKGROUND: Gastric cancer (GC) is the third most common cancer in India and is mediated by multiple genetic, epigenetic and environmental risk factors. A single nucleotide polymorphism rs3025058 at -1171 of the stromelysin-1 (matrix metalloproteinase [MMP]-3) promoter is resulting due to insertion/deletion of adenine thought to have an impact on increasing the risk for tumor formation. AIM: This study is aimed...
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