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Article

Downregulation of SPARC expression decreases gastric cancer cellular invasion and survival

2 Jun 2010

Abstract excerpt

BACKGROUND: Secreted protein acidic and rich in cysteine (SPARC) plays a key role in the development of many tissues and organ types. Aberrant SPARC expression was found in a wide variety of human cancers, contributes to tumor development. Because SPARC was found to be overexpressed in human gastric cancer tissue, we therefore to explore the expression of SPARC in gastric cancer lines and the carcinogenic...

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PMID: 20525171
DOI: 10.1186/1756-9966-29-59

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