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Article

Heme oxygenase-1 regulates the immune response to influenza virus infection and vaccination in aged mice.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Jul 2012

Cummins Nathan W, Weaver Eric A, May Shannon M, Croatt Anthony J, Foreman Oded, Kennedy Richard B, Poland Gregory A, Barry Michael A, Nath Karl A, Badley Andrew D

Abstract excerpt

Underlying mechanisms of individual variation in severity of influenza infection and response to vaccination are poorly understood. We investigated the effect of reduced heme oxygenase-1 (HO-1) expression on vaccine response and outcome of influenza infection. HO-1-deficient and wild-type (WT) mi...

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Identifiers

PMID: 22490782
DOI: 10.1096/fj.11-190017
PMCID: PMC3382093

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22490782-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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