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Article

Comprehensive evaluation of the impact of 14 genetic variants on colorectal cancer phenotype and risk.

American journal of epidemiology - 1 Jan 2012

Lubbe Steven J, Di Bernardo Maria Chiara, Broderick Peter, Chandler Ian, Houlston Richard S

Abstract excerpt

To comprehensively evaluate the impact of recently identified colorectal cancer (CRC) variants at 1q41, 3q26.2, 8q23.3, 8q24.21, 10p14, 11q23.1, 12q13.13, 14q22.2, 15q13.3, 16q22.1, 18q21.1, 19q13.11, 20p12.3, and 20q13.33 on risk and CRC phenotype, the authors analyzed 8,878 cases and 6,051 controls from the United Kingdom ascertained in 1999-2007. The impact of variants on the familial CRC risk was enumerated...

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Identifiers

PMID: 22156018
DOI: 10.1093/aje/kwr285

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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