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Article

Head-to-Head Comparison of Family History of Colorectal Cancer and a Genetic Risk Score for Colorectal Cancer Risk Stratification.

Clinical and translational gastroenterology - 1 Dec 2019

Weigl Korbinian, Hsu Li, Knebel Phillip, Hoffmeister Michael, Timofeeva Maria, Farrington Susan, Dunlop Malcolm, Brenner Hermann

Abstract excerpt

OBJECTIVES: Family history (FH) is associated with increased risk of colorectal cancer (CRC). We aimed to examine the potential for CRC risk stratification by known common genetic variants beyond FH in a large population-based case-control study from Germany. METHODS: Four thousand four hundred forty-seven cases and 3,480 controls recruited in 2003-2016 were included for whom comprehensive interview, medical, and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 31800541
DOI: 10.14309/ctg.0000000000000106
PMCID: PMC6970558

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