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Article

Notch signals in the endothelium and cancer "stem-like" cells: opportunities for cancer therapy

1 Jan 2012

Abstract excerpt

Anti-angiogenesis agents and the identification of cancer stem-like cells (CSC) are opening new avenues for targeted cancer therapy. Recent evidence indicates that angiogenesis regulatory pathways and developmental pathways that control CSC fate are intimately connected, and that endothelial cells are a key component of the CSC niche. Numerous anti-angiogenic therapies developed so far target the VEGF pathway....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 22487493
DOI: 10.1186/2045-824x-4-7

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