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Roles of endothelial cell specific molecule‑1 in tumor angiogenesis (Review)

1 Feb 2024

Abstract excerpt

Angiogenesis plays a crucial role in tumor growth and metastasis, and is heavily influenced by the tumor microenvironment (TME). Endothelial cell dysfunction is a key factor in tumor angiogenesis and is characterized by the aberrant expression of pro-angiogenic factors. Endothelial cell specific molecule-1 (ESM1), also known as endocan, is a marker of endothelial cell dysfunction. Although ESM1 is primarily...

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PMID: 38357478
DOI: 10.3892/ol.2024.14270

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