Article
Hallmarks in colorectal cancer: Angiogenesis and cancer stem-like cells
1 Jan 2014
Abstract excerpt
Carcinogenesis is a multistep process that requires the accumulation of various genetic and epigenetic aberrations to drive the progressive malignant transformation of normal human cells. Two major hallmarks of carcinogenesis that have been described are angiogenesis and the stem cell characteristic of limitless replicative potential. These properties have been targeted over the past decade in the development of...
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