Article
Pilot candidate gene analysis of patients ≥ 60 years old with aortic stenosis involving a tricuspid aortic valve.
The American journal of cardiology - 1 Jul 2012
Ellis Stephen G, Dushman-Ellis Sandra, Luke May M, Murugesan Gurunathan, Kottke-Marchant Kandice, Ellis Gary M, Griffin Brian, Tuzcu E Murat, Hazen Stanley
Abstract excerpt
The potential genetic basis of aortic stenosis in older people is poorly understood. A total of 265 patients with aortic stenosis involving tricuspid aortic valves and 961 controls were genotyped for ≤660 candidate single nucleotide polymorphisms (SNPs). After dividing the patients and controls into training and validation sets, we tested the correlation of the SNPs with the age-adjusted aortic valve area,...
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