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Article

Replication of genetic association studies in aortic stenosis in adults.

The American journal of cardiology - 1 Nov 2011

Gaudreault Nathalie, Ducharme Valérie, Lamontagne Maxime, Guauque-Olarte Sandra, Mathieu Patrick, Pibarot Philippe, Bossé Yohan

Abstract excerpt

Only a handful of studies have attempted to unravel the genetic architecture of calcific aortic valve stenosis (AS). The goal of this study was to validate genes previously associated with AS. Seven genes were assessed: APOB, APOE, CTGF, IL10, PTH, TGFB1, and VDR. Each gene was tested for a comprehensive set of single-nucleotide polymorphisms (SNPs). SNPs were genotyped in 457 patients who underwent surgical...

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Share to Aortic Valve Stenosis
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21855833
DOI: 10.1016/j.amjcard.2011.06.050

Genes

APOB
PTH
TGFB1
VDR
APOE

Variants

rs1042031

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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