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Article

Disrupted-in-schizophrenia (DISC1) functions presynaptically at glutamatergic synapses.

PloS one - 1 Jan 2012

Maher Brady J, LoTurco Joseph J

Abstract excerpt

The pathophysiology of schizophrenia is believed to involve defects in synaptic transmission, and the function of many schizophrenia-associated genes, including DISC1, have been linked to synaptic function at glutamatergic synapses. Here we develop a rodent model via in utero electroporation to a...

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Source

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Identifiers

PMID: 22479520
DOI: 10.1371/journal.pone.0034053
PMCID: PMC3316587

Genes

DISC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22479520-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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