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Article

High rates of ras codon 61 mutation in thyroid tumors in an iodide-deficient area.

Cancer research - 15 May 1991

Shi Y F, Zou M J, Schmidt H, Juhasz F, Stensky V, Robb D, Farid N R

Abstract excerpt

Using polymerase chain reaction and sequence-specific oligonucleotide hybridization, the frequency of three ras oncogene mutations (N-ras, Ha-ras, and K-ras) in thyroid tumors (25 adenomas, 16 follicular carcinomas, and 22 papillary carcinomas) was investigated in both iodide-deficient and iodide-sufficient areas. The ras oncogene mutation rate was significantly higher in the iodide-deficient area, being 85...

Topics

Adenocarcinoma
Adenoma
Carcinoma, Papillary
Codon
Genes, ras
Humans
Hungary
Iodine
Mutation
Thyroid Neoplasms

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 2021946

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2021946-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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