Article
Molecular genetic study comparing follicular variant versus classic papillary thyroid carcinomas: association of N-ras mutation in codon 61 with follicular variant.
Human pathology - 1 Jul 2006
Di Cristofaro Julie, Marcy Myriam, Vasko Vasily, Sebag Frédéric, Fakhry Nicolas, Wynford-Thomas David, De Micco Catherine
Abstract excerpt
Although the follicular variant of papillary thyroid carcinoma (FVPTC) has been classified as a papillary cancer based on nuclear features, its follicular growth pattern and potential for hematogenous spread are more characteristic of follicular carcinoma. To gain insight into the biologic nature of FVPTC, we compared genetic alterations characteristic of papillary and follicular thyroid carcinomas in 24 FVPTCs...
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