Article
A functional haplotype of UBE2L3 confers risk for systemic lupus erythematosus.
Genes and immunity - 1 Jul 2012
Wang S, Adrianto I, Wiley G B, Lessard C J, Kelly J A, Adler A J, Glenn S B, Williams A H, Ziegler J T, Comeau M E, Marion M C, Wakeland B E, Liang C, Kaufman K M, Guthridge J M, Alarcón-Riquelme M E, Alarcón G S, Anaya J-M, Bae S-C, Kim J-H, Joo Y B, Boackle S A, Brown E E, Petri M A, Ramsey-Goldman R, Reveille J D, Vilá L M, Criswell L A, Edberg J C, Freedman B I, Gilkeson G S, Jacob C O, James J A, Kamen D L, Kimberly R P, Martin J, Merrill J T, Niewold T B, Pons-Estel B A, Scofield R H, Stevens A M, Tsao B P, Vyse T J, Langefeld C D, Harley J B, Wakeland E K, Moser K L, Montgomery C G, Gaffney P M
Abstract excerpt
Systemic lupus erythematosus (SLE) is an autoimmune disease with diverse clinical manifestations characterized by the development of pathogenic autoantibodies manifesting in inflammation of target organs such as the kidneys, skin and joints. Genome-wide association studies have identified genetic...
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