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Article

The autoimmune disease risk allele of UBE2L3 in African American patients with systemic lupus erythematosus: a recessive effect upon subphenotypes.

The Journal of rheumatology - 1 Jan 2012

Agik Sandra, Franek Beverly S, Kumar Akaash A, Kumabe Marissa, Utset Tammy O, Mikolaitis Rachel A, Jolly Meenakshi, Niewold Timothy B

Abstract excerpt

OBJECTIVE: UBE2L3 is associated with susceptibility to systemic lupus erythematosus (SLE) and rheumatoid arthritis in European ancestry populations, and this locus has not been investigated fully in non-European populations. We studied the UBE2L3 risk allele for association with SLE, interferon-α (IFN-α), and autoantibodies in a predominantly African American SLE cohort. METHODS: We studied 395 patients with SLE...

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Identifiers

PMID: 22045845
DOI: 10.3899/jrheum.110590
PMCID: PMC3304461

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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