Article
Consistent directions of effect for established type 2 diabetes risk variants across populations: the population architecture using Genomics and Epidemiology (PAGE) Consortium.
Diabetes - 1 Jun 2012
Haiman Christopher A, Fesinmeyer Megan D, Spencer Kylee L, Buzková Petra, Voruganti V Saroja, Wan Peggy, Haessler Jeff, Franceschini Nora, Monroe Kristine R, Howard Barbara V, Jackson Rebecca D, Florez Jose C, Kolonel Laurence N, Buyske Steven, Goodloe Robert J, Liu Simin, Manson Joann E, Meigs James B, Waters Kevin, Mukamal Kenneth J, Pendergrass Sarah A, Shrader Peter, Wilkens Lynne R, Hindorff Lucia A, Ambite Jose Luis, North Kari E, Peters Ulrike, Crawford Dana C, Le Marchand Loic, Pankow James S
Abstract excerpt
Common genetic risk variants for type 2 diabetes (T2D) have primarily been identified in populations of European and Asian ancestry. We tested whether the direction of association with 20 T2D risk variants generalizes across six major racial/ethnic groups in the U.S. as part of the Population Arc...
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