Article
Consistent association of type 2 diabetes risk variants found in europeans in diverse racial and ethnic groups.
PLoS genetics - 26 Aug 2010
Waters Kevin M, Stram Daniel O, Hassanein Mohamed T, Le Marchand Loïc, Wilkens Lynne R, Maskarinec Gertraud, Monroe Kristine R, Kolonel Laurence N, Altshuler David, Henderson Brian E, Haiman Christopher A
Abstract excerpt
It has been recently hypothesized that many of the signals detected in genome-wide association studies (GWAS) to T2D and other diseases, despite being observed to common variants, might in fact result from causal mutations that are rare. One prediction of this hypothesis is that the allelic assoc...
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