Article
The Next PAGE in understanding complex traits: design for the analysis of Population Architecture Using Genetics and Epidemiology (PAGE) Study.
American journal of epidemiology - 1 Oct 2011
Matise Tara C, Ambite Jose Luis, Buyske Steven, Carlson Christopher S, Cole Shelley A, Crawford Dana C, Haiman Christopher A, Heiss Gerardo, Kooperberg Charles, Marchand Loic Le, Manolio Teri A, North Kari E, Peters Ulrike, Ritchie Marylyn D, Hindorff Lucia A, Haines Jonathan L
Abstract excerpt
Genetic studies have identified thousands of variants associated with complex traits. However, most association studies are limited to populations of European descent and a single phenotype. The Population Architecture using Genomics and Epidemiology (PAGE) Study was initiated in 2008 by the National Human Genome Research Institute to investigate the epidemiologic architecture of well-replicated genetic variants...
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