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Article

Multi-ethnic GWAS and fine-mapping of glycaemic traits identify novel loci in the PAGE Study.

Diabetologia - 1 Mar 2022

Downie Carolina G, Dimos Sofia F, Bien Stephanie A, Hu Yao, Darst Burcu F, Polfus Linda M, Wang Yujie, Wojcik Genevieve L, Tao Ran, Raffield Laura M, Armstrong Nicole D, Polikowsky Hannah G, Below Jennifer E, Correa Adolfo, Irvin Marguerite R, Rasmussen-Torvik Laura J F, Carlson Christopher S, Phillips Lawrence S, Liu Simin, Pankow James S, Rich Stephen S, Rotter Jerome I, Buyske Steven, Matise Tara C, North Kari E, Avery Christy L, Haiman Christopher A, Loos Ruth J F, Kooperberg Charles, Graff Mariaelisa, Highland Heather M

Abstract excerpt

AIMS/HYPOTHESIS: Type 2 diabetes is a growing global public health challenge. Investigating quantitative traits, including fasting glucose, fasting insulin and HbA1c, that serve as early markers of type 2 diabetes progression may lead to a deeper understanding of the genetic aetiology of type 2 diabetes development. Previous genome-wide association studies (GWAS) have identified over 500 loci associated with type...

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Identifiers

PMID: 34951656
DOI: 10.1007/s00125-021-05635-9
PMCID: PMC8810722

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GCK

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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