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Article

Quantification of the calcification phenotype of Abcc6-deficient mice with microcomputed tomography.

The American journal of pathology - 1 Jun 2012

Le Corre Yannick, Le Saux Olivier, Froeliger Florence, Libouban Hélène, Kauffenstein Gilles, Willoteaux Serge, Leftheriotis Georges, Martin Ludovic

Abstract excerpt

Pseudoxanthoma elasticum in humans and dystrophic cardiac calcification in mice are heritable disorders characterized by dystrophic calcification of soft connective tissues related to the defective function of the ABCC6 (human)/Abcc6 (mouse) transporter. Of particular interest is the finding of calcified vibrissae in Abcc6(-/-) mice, which facilitates the study of dystrophic calcification by histological...

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Source

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Identifiers

PMID: 22469843
DOI: 10.1016/j.ajpath.2012.02.007
PMCID: PMC5691325

Genes

ABCC6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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