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Article

Pseudoxanthoma elasticum, the paradigm of heritable ectopic mineralization disorders - can diet help?

Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG - 1 Aug 2011

LaRusso Jennifer, Li Qiaoli, Uitto Jouni

Abstract excerpt

Pseudoxanthoma elasticum (PXE) is a heritable multi-system disorder manifesting with characteristic cutaneous lesions, associated with ocular findings and cardiovascular involvement. The skin lesions, yellowish papules which coalesce into plaques of inelastic and leathery skin, demonstrate by histopathologic and ultrastructural examinations ectopic mineralization of dermal connective tissues, primarily the...

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Identifiers

PMID: 21435181
DOI: 10.1111/j.1610-0387.2011.07658.x
PMCID: PMC3307339

Genes

ABCC6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Pseudoxanthoma elasticum, the paradigm of heritable ectopic mineralization disorders - can diet help?PMID 21435181Read ↗

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Pseudoxanthoma elasticum and skin: Clinical manifestations, histopathology, pathomechanism, perspectives of treatmentSemantic proximity Read ↗

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Abcc6 Knockout Rat Model Highlights the Role of Liver in PPi Homeostasis in Pseudoxanthoma Elasticum.Semantic proximity Read ↗

Pseudoxanthoma elasticum: molecular genetics and putative pathomechanisms.Semantic proximity Read ↗

Pseudoxanthoma elasticum: progress in diagnostics and research towards treatment : Summary of the 2010 PXE International Research Meeting.Semantic proximity Read ↗

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The mineralization phenotype in Abcc6 ( -/- ) mice is affected by Ggcx gene deficiency and genetic background--a model for pseudoxanthoma elasticum.Semantic proximity Read ↗

ABCC6 prevents ectopic mineralization seen in pseudoxanthoma elasticum by inducing cellular nucleotide release.Semantic proximity Read ↗

Insights into Pathomechanisms and Treatment Development in Heritable Ectopic Mineralization Disorders: Summary of the PXE International Biennial Research Symposium-2016.Semantic proximity Read ↗

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