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Article

The molecular and physiological roles of ABCC6: more than meets the eye

1 Jan 2012

Abstract excerpt

Abnormal mineralization occurs in the context of several common conditions, including advanced age, diabetes, hypercholesterolemia, chronic renal failure, and certain genetic conditions. Metabolic, mechanical, infectious, and inflammatory injuries promote ectopic mineralization through overlapping yet distinct molecular mechanisms of initiation and progression. The ABCC6 protein is an ATP-dependent transporter...

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PMID: 23248644
DOI: 10.3389/fgene.2012.00289

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