Article
The ABCC6 transporter: what lessons can be learnt from other ATP-binding cassette transporters?
1 Jan 2013
Abstract excerpt
ABC transporters represent a large family of ATP-driven transmembrane transporters involved in uni- or bidirectional transfer of a large variety of substrates. Divided in seven families, they represent 48 transporter proteins, several of which have been associated with human disease. Among the latter is ABCC6, a unidirectional exporter protein primarily expressed in liver and kidney. ABCC6 deficiency has been...
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