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Article

EGFR mutations detection on liquid-based cytology: is microscopy still necessary?

Journal of clinical pathology - 1 Jun 2012

Malapelle Umberto, de Rosa Nicla, Bellevicine Claudio, Rocco Danilo, Vitiello Fabiana, Piantedosi Franco Vito, Illiano Alfonso, Nappi Oscar, Troncone Giancarlo

Abstract excerpt

Currently, there is a trend towards an increasing use of liquid-based cytology (LBC) to diagnose non-small cell lung cancer. In this study, to detect epidermal growth factor receptor mutations, different molecular techniques were applied to LBC samples with and without laser capture microdissection (LCM). In 58 LBCs, DNA was extracted twice. One sample was obtained directly from CytoLyt solution, whereas the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22466414
DOI: 10.1136/jclinpath-2011-200659

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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